G-Protein β3 Subunit Gene ( GNB3 ) Variant in Causation of Essential Hypertension

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G protein beta3 subunit variant and essential hypertension in Japanese.

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Prediction of the Risk for Essential Hypertension among Carriers of C825T Genetic Polymorphism of G Protein β3 (GNB3) Gene

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genetic susceptibility of angiotensin-i converting enzyme and g-protein β3-subunit gene polymorphisms to essential hypertension

essential hypertension (eh) accounts for 90-95% of hypertension cases. eh, as a progressive cardiovascular syndrome arising from complex and interrelated etiologies, results from combined and interactive effects of genetic and environmental factors. the objective was to investigate the ace i/d and gnb3 c825t polymorphisms and both genotypes combined with seeking gene-gene interactions to furthe...

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G-Protein b3 Subunit Gene Variant and Left Ventricular Hypertrophy in Essential Hypertension

A functional genetic variant consisting of a C825T substitution in the GNB3 gene, encoding for the G-protein b3 subunit, has been associated with enhanced G-protein activation and cell growth. The aim of the study was to investigate the association of this polymorphism with left ventricular hypertrophy (LVH) in a sample of patients with essential hypertension. Left ventricular mass was assessed...

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A functional genetic variant consisting of a C825T substitution in the GNB3 gene, encoding for the G-protein beta(3) subunit, has been associated with enhanced G-protein activation and cell growth. The aim of the study was to investigate the association of this polymorphism with left ventricular hypertrophy (LVH) in a sample of patients with essential hypertension. Left ventricular mass was ass...

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ژورنال

عنوان ژورنال: Hypertension

سال: 1998

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.32.6.1094